The Long-Term Impact of Therapeutic Fasting on Primary Dysmenorrhea in Young Female Adults: A Randomized Controlled Trial.

Background and objective Primary dysmenorrhea (PD) is one of the leading health issues among women. According to reports, nutrition/diet significantly affects the severity and course of PD. The present study aimed to evaluate the role of therapeutic fasting in alleviating the symptoms associated with PD, improving quality of life (QoL), and reducing absenteeism among young female adults with PD. Methods A total of 52 participants aged between 18 and 24 years were included in the study and randomly classified into two groups of 26 each. The study group (fasting group) was assigned to undergo a 10-day fasting regimen (≤500 kcal/day) while the control group was to follow a normal dietary routine. The severity of pain, associated distress symptoms, QoL, and sleep quality were measured at baseline and on the fifth day of the first, second, and third menstruation cycles after the intervention, using the Visual Analog Scale (VAS), Numerical Rating Scale (NRS), the World Health Organization Quality of Life Brief Version (WHOQOL-BREF) questionnaire, and Pittsburg Sleep Quality Index. We also recorded the rate of absenteeism among the study participants during menstruation cycles. Results We observed a significant reduction in pain (p<0.001), cramps (p=0.001), nausea/vomiting (p=0.02), dizziness (p=0.007), and mood changes (p=0.005) in the study group compared to the control group. The effects were persistent in most of the variables at the second and third follow-ups as well. The physical (p=0.005) and psychological (p<0.001) QoL significantly improved in the first month, and we observed a similar trend at the second (physical p=0.03; psychological p=0.001) and third follow-ups (psychological p=0.002) except for physical QoL, which was significant only at the second follow-up. The fasting group had significantly lower absenteeism compared to the controls during the first follow-up (p=0.001). Conclusion Therapeutic fasting may be considered a safe and effective option in the management of PD. Future trials should examine the long-term sustainability of the results.

Unity of Disease and Unity of Cure: An Evidence-based Perspective.

Context: One of the governing principles of naturopathic medicine is the concept of Unity of Disease and Unity of Cure (UDUC). Many naturopathic physicians and students find it challenging to provide a scientific basis for UDUC because conventionally every disease has varying etiologies. Objective: The review intended to explore the basis of UDUC, examining the available theoretical evidence around this fundamental tenet of naturopathic medicine, to promote its effective use when consulting new patients and planning the subsequent treatment. Design: The research team performed a narrative review by searching PubMed, PubMed central, Scopus, Google scholar databases, textbooks on naturopathy and websites of professional bodies representing naturopathic medicine. The search used the keywords 'Naturopathic Medicine', 'Naturopathy', 'Holism', 'Self-healing', 'Pyschosocial determinants and health', 'unity of disease and unity of cure', 'health and disease', 'Multi-model approach', 'whole-system practice' and 'Global naturopathic practice'. Setting: The review took place at Sant Hirdaram Medical College of Naturopathy and Yogic Sciences for women in Bhopal, Madhya Pradesh, India. Results: The present review provides a comprehensive overview of the scientific evidence behind UDUC under four layers: psychological factors, lifestyle factors, physiological alterations, and disease manifestation. The data presented in this review substantiate the presence of these four layers in the manifestation of various clinical conditions like musculoskeletal disorders, obstetric and gynecological disorders, cardiometabolic disorders, infectious disorders, and gastrointestinal disorders. Conclusions: It's very evident that the global naturopathic profession embraces traditional philosophies as the core of their practices. However, the field needs measures, such as the formulation of international working groups and the organization of continuous medical-education programs, congresses, and exchange programs, to facilitate crosstalk among practitioners from different parts of the world, which may assert the importance of philosophical tenets such as UDUC in clinical practice.

Patient-centric holistic integrative therapies as an adjuvant in checking the progression of chronic kidney disease: A case study.

OBJECTIVE: Chronic kidney diseases (CKDs) characterized by progressive loss of kidney function impart significant burden on the patients. Besides physical disabilities, CKD affects the mental health and quality of life of the patients. Recent studies suggest the need for interdisciplinary patient-centric care in the management of CKD. METHODS: The present study introduced patient-centric holistic integrative therapies (YNBLI) in a 64-year-old female diagnosed with CKD in 2021, who presented with breathlessness, fatigue, loss of appetite, and anxiety. She is a known case of type 2 diabetes, hypertension and osteoarthritis of knee. She was advised for dialysis by her nephrologists', however, she was reluctant to undergo dialysis due to anxiety about the side effects and lifelong dependency on dialysis. She initially underwent a 10-day YNBLI program at our inpatient setting followed by adhering to the home-based YNBLI for 16 weeks. RESULTS: She showed significant improvement in the kidney function, hemoglobin levels, quality of life and symptoms with no adverse events. The improvements were consistent throughout the 16 weeks after discharge. DISCUSSION: This study presents the effective use of patient-centric holistic integrative therapies (YNBLI) as an adjuvant in the management of CKD. Future studies are warranted to substantiate these findings.

Is delayed regulation of yoga and naturopathic medicine in India breeding quackery?

The combined discipline of Yoga & Naturopathy (Y&N) constitutes one of the official indigenous medical systems under the Ministry of Ayurveda, Yoga & Naturopathy, Unani, Siddha, Sowa-Rigpa, and Homoeopathy (AYUSH), Government of India (GoI). The GoI has recently regulated all the systems under AYUSH, except Yoga & Naturopathy, through the National Commission for Indian System of Medicine (NCISM) Bill, 2020 [1]. However, Y&N has been left out from the NCISM Bill, despite the recommendations of the Department-related Parliamentary Standing Committee on the National Commission for Indian System of Medicine Bill, 2019 [2: p 20], and NITI Aayog [3: p 15]. On the contrary, GoI has proposed a board for regulating Y&N without defining its statutory value or timeline.

Effect of Medically Supervised Prolonged Fasting Therapy on Vitamin D, B12, Body Weight, Body Mass Index, Vitality and Quality of Life: A Randomized Control Trial.

Background: Recent research indicates prolonged fasting for more than 7 days is beneficial in priming the vitamin D metabolism. However, methodological limitations in previous studies, such as insufficient sample size and a lack of control group, limits its generalizability. The present study evaluated the impact of prolonged fasting (10 days) on vitamin D, vitamin B12, body mass index (BMI), weight, hemoglobin, vitality and quality of life (QoL) compared to a normal diet. Methods: This randomized control trial was conducted in an in-patient private yoga and naturopathy setting between February and April 2022. A total of 52 participants (mean age 51.57 ± 13.67 years) with varying medical conditions were randomized into a fasting group (FG) or a normal diet group (NDG) with 26 participants in each group. The FG was on a fasting diet (500 kCal/day) which included holy basil herbal tea, lemon honey water, and water (3 L). The NDG (1500 kCal/day) consumed a routine diet that included Indian bread, pulses, steamed rice, vegetable salads, and beverages. Results: The FG has shown significant increase in the Vitamin D levels (P = .003, d = 0.475), vitality (P = .006, d = 0.425), physical QoL (P < .001, d = 0.549), psychological QoL (P = .002, d = 0.488), and environmental QoL (P = .004, d = 0.457) compared to NDG. No significant changes were observed in vitamin B12, weight, BMI, haemoglobin, and social QoL. A weak to moderate (ρ = 0.330-0.483) positive correlation was observed between vitality scores and QoL domains, whereas BMI scores showed an inverse correlation (ρ = -.280) with vitamin D levels. Conclusion: The results suggest that prolonged fasting for 10 days can improve vitamin D levels, improve vitality, and promote quality of life compared to a normal diet. Unlike previous studies, the FG does not differ from the NDG concerning weight and BMI. Nevertheless, fasting may be utilized as an effective tool to tackle vitamin D deficiency and associated health insufficiencies.

Outcomes of a Medically Supervised Fasting Module on Healthy Females in a Controlled Residential Environment: A Brief Report.

BACKGROUND: Fasting is being used as a therapeutic and cultural practice for millennia. There are numerous reports available on beneficial effects of fasting on various disease conditions. Despite the mounting evidence on fasting, little is known on its physiological effects in humans as most of the studies on physiological effects are done in animals. METHODS: Twenty healthy female volunteers (mean age ± SD, 21.95 ± 2.52 years) participated in a 10-day fasting program, which has 1 preparatory day and 1 refeeding day (1,000 kcal) and 8 fasting days (500 kcal). All the participants consented to participate in the study. Blood parameters like complete blood count, renal function test, total iron binding capacity, lipid profile, liver profile, vitamins D and B12, thyroid function tests, glycated hemoglobin, and air blood gas test along with anthropometric measurements were taken on the first and last day. RESULTS: All the parameters under the study have shown statistically significant changes (p < 0.05) except hemoglobin (p = 0.7) and non-high density lipoprotein (p = 0.32). Notable changes were the significant increase in vitamins D and B12 levels that signifies the homoeostatic potential of a fasting regimen. CONCLUSION: The result depicts the positive impact of fasting on various physiological parameters that warrants further studies on the safety of fasting in diverse diseases, especially the ones that have metabolic disarray as the root cause. Despite the limitation of the smaller sample size and lack of a control group, the results are encouraging to devise disease-specific fasting programs.

Effects of naturopathy and yoga intervention on CD4 count of the individuals receiving antiretroviral therapy-report from a human immunodeficiency virus sanatorium, Pune.

BACKGROUND: Human immunodeficiency virus (HIV) infection is one of the most debilitating conditions which have affected nearly 32 million people across the globe. Antiretroviral therapy (ART) is the standard care given to the HIV positive individuals. But the patient adherence to ART is found to be very less as per previous studies. Complementary and alternative medicine is becoming a pillar in the rehabilitative efforts for many living with HIV/AIDS. AIM: To evaluate the effect of naturopathy and yoga intervention on CD4 counts of HIV patients. METHODS: Ninety-six patients prediagnosed as HIV positive were enrolled after obtaining written consent and treated with naturopathy and yoga interventions like hydrotherapy, diet therapy, mud therapy, counseling, etc., for various durations at National Institute of Naturopathy Sanatorium. They were grouped into four groups (G1: 1-7 days, G2: 8-15 days, G3: 16-30 days, G4: >30 days) based on duration of stay. CD4 count of each individual was recorded pre- and post-stay. RESULTS: All analyses were conducted using R package version 3.01. Dependent sample t-tests were conducted to examine the significance at 95% confidence interval. Of the 96 patients, male patients constitute 55.2% and female patients 44.8% with mean age 34.74 received 1-180 days (mean 28.75, standard deviation: 14.16) treatment. Significant increase in the CD4 count was observed in two out of the four groups (G2: P = 0.052, and G4: P = 0.00038, respectively). CONCLUSION: An increasing trend in the CD4 count was observed that was proportional to the length of the stay of participants at the HIV sanatorium. This indicates the possibility of lifestyle changes can bring positive outcomes in people living with HIV/AIDS when used as an adjuvant with ART care. The lack of control group is a major limitation of this study. No attempt was made to study the subjective changes in the quality of life, viral load, etc., However, larger controlled studies are warranted for conclusive results.